2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-177337
    N-Didesmethyladitoprim
    N-Didesmethyladitoprim is a metabolite of Aditoprime (HY-139743). Aditoprime is a selective bacterial dihydrofolate reductase (DHFR) inhibitor with IC50s of 47 and 520 nM for E.coli and L.casei DHFR , respectively. Aditoprime inhibits the transformation of dihydrofolic acid to tetrahydrofolic acid. Aditoprime has a broad-spectrum antibacterial activity and excellent pharmacokinetics.
    N-Didesmethyladitoprim
  • HY-118025R
    (±)-2-Oxo clopidogrel (Standard)
    (±)-2-Oxo clopidogrel (Standard) is the analytical standard of (±)-2-Oxo clopidogrel. This product is intended for research and analytical applications. (±)-2-Oxo clopidogrel is a metabolite of the antiplatelet agent Clopidogrel (HY-15283).
    (±)-2-Oxo clopidogrel (Standard)
  • HY-W004412
    Olanzapine-lactam
    		99.12%
    Olanzapine-lactam (LY301664) is a metabolite of Olanzapine (HY-14541).
    Olanzapine-lactam
  • HY-W587982
    1-(7-Hydroxy-4-methyloctyl) 1,2-cyclohexanedicarboxylate
    1-(7-Hydroxy-4-methyloctyl) 1,2-cyclohexanedicarboxylate is a metabolite of di (isononyl) cyclohexane-1,2-dicarboxylate (DINCH) , an alternative for phthalate plasticizers. It can be used as a biomarker of exposure to DINCH.
    1-(7-Hydroxy-4-methyloctyl) 1,2-cyclohexanedicarboxylate
  • HY-172054
    PB-22 N-(4-Hydroxypentyl)-3-carboxyindole metabolite
    PB-22 N-(4-Hydroxypentyl)-3-carboxyindole metabolite is a metabolite of PB-22. PB-22 is a cannabinoid.
    PB-22 N-(4-Hydroxypentyl)-3-carboxyindole metabolite
  • HY-131275R
    Imatinib Impurity E (Standard)
    Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
    Imatinib Impurity E (Standard)
  • HY-W701936
    2-O-Desmethyl cisapride
    2-O-Desmethyl cisapride is a minor Cisapride metabolite.
    2-O-Desmethyl cisapride
  • HY-19657R
    Oxypurinol (Standard)
    Oxypurinol (Standard) is the analytical standard of Oxypurinol. This product is intended for research and analytical applications. Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
    Oxypurinol (Standard)
  • HY-A0111R
    Cefetamet (Standard)
    Cefetamet (Standard) is the analytical standard of Cefetamet (HY-A0111). This product is intended for research and analytical applications. Cefetamet (Ro 15-8074) is a cephalosporin antibiotic and the active metabolite of Cefetamet pivoxil (HY-B1894A). Cefetamet binds to bacterial penicillin-binding protein (PBP) (IC50 for PBP3 in Escherichia coli W3110 is 2.5 μg/mL). Cefetamet has significant activity against Gram-negative bacteria such as Enterobacteriaceae, Neisseria species, and Haemophilus influenzae, as well as Gram-positive bacteria such as Streptococcus. Cefetamet kills and lyses Treponema pallidum. Cefetamet can be used in the research of respiratory tract, urinary tract, ear, nose and throat infections, and syphilis.
    Cefetamet (Standard)
  • HY-W424779R
    5-Carboxy-2′-deoxyuridine (Standard)
    5-Carboxy-2′-deoxyuridine (Standard) is the analytical standard of 5-Carboxy-2′-deoxyuridine. This product is intended for research and analytical applications. 5-Carboxy-2′-deoxyuridine is a metabolite of Trifluridine. 5-Carboxy-2′-deoxyuridine is a methyl oxidation product of Thymidine that can be formed by menadione-mediated photosensitization of Thymidine.
    5-Carboxy-2′-deoxyuridine (Standard)
  • HY-135194R
    Risperidone E-oxime (Standard)
    Risperidone E-oxime (Standard) is the analytical standard of Risperidone E-oxime. This product is intended for research and analytical applications. Risperidone E-oxime is an impurity of Risperidone. Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively .
    Risperidone E-oxime (Standard)
  • HY-165423
    DM-4111
    DM-4111, one of the major monohydroxyl metabolites of Tolvaptan (HY-17000), is a potent vasopressin V2 receptor inhibitor. DM-4111 inhibits water reabsorption in the renal tubules, thereby promoting the excretion of electrolyte-free water. DM-4111 is promising for research of cardiovascular diseases.
    DM-4111
  • HY-W017464R
    NAPQI (Standard)
    NAPQI (Standard) is the analytical standard of NAPQI (HY-W017464). This product is intended for research and analytical applications. NAPQI is the toxic metabolite of Acetaminophen (HY-66005). NAPQI is also an inhibitor of enzymes in the vitamin K cycle. NAPQI is rapidly detoxified by glutathione (GSH), but in situations of GSH deficiency, excess NAPQI reacts with cysteine residues in proteins, causing cell death and toxicity in the liver.
    NAPQI (Standard)
  • HY-137532S
    7-Hydroxy Quetiapine-d8
    7-Hydroxy Quetiapine-d8 is the deuterium labeled 7-Hydroxyquetiapine. 7-Hydroxyquetiapine (ICI 214227) is the major active metabolite of antipsychotic medicine Quetiapine.
    7-Hydroxy Quetiapine-d<sub>8</sub>
  • HY-164920
    WR 199507 trihydrobromide
    WR 199507 trihydrobromide, a putative Primaquine (HY-12651A) metabolite, causes methemoglobin formation in canine hemolysates.
    WR 199507 trihydrobromide
  • HY-169464
    Cannabinol-7-oic acid
    Cannabinol-7-oic acid is a metabolite of cannabinol that can be found in faeces.
    Cannabinol-7-oic acid
  • HY-W353006
    Desmethyl lacosamide
    Desmethyl lacosamide is a metabolite of Lacosamide (an antiepileptic compound).
    Desmethyl lacosamide
  • HY-W035375
    Mephedrone metabolite hydrochloride ((±)-ephedrine stereochemistry)
    		Control
    Mephedrone metabolite hydrochloride ((±)-ephedrine stereochemistry) is a metabolite of Mephedrone.
    Mephedrone metabolite hydrochloride ((±)-ephedrine stereochemistry)
  • HY-177977
    4-Hydroxyalprenolol
    4-Hydroxyalprenolol (Alp2b) is a metabolite of β-receptor blocker Alprenolol (HY-B1517).
    4-Hydroxyalprenolol
  • HY-175054
    Para-hydroxy 2-methyl AP-237 hydrochloride
    Para-hydroxy 2-methyl AP-237 (4'-Hydroxy 2-methyl AP-237, p-Hydroxy 2-methyl AP-237) hydrochloride is a metabolite of 2-methyl AP-237.
    Para-hydroxy 2-methyl AP-237 hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity